"Frankly most of the stuff we try just doesn't work"
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"We replaced the wave length of the light by the wave length of electrons at an accelerating voltage of 75 kV and inserted into the Abbe relation the imaging accelerating voltage of 75 kV and inserted into the Abbe relation the imaging accelerating voltage of 75 kV and inserted into the Abbe relation the imaging aperture of 2 X 10-2 rad...we came up with a resolution limit of 2.2 Å ."
"I didn't know enough diffraction theory to even know why what I was doing wouldn't work. That was a problem. I was too much of an empiricist at the time. I learned later that it's better to know what you are doing."
"... fluorescence microscopy in its early years was considered a specialized method which, in the opinion of some, was doomed to fail. "
"Our work, it seems to me, can bring us a special bonus of pleasure and satisfaction, through its very close contact with colleagues of different disciplines and our ability to peep into the inexhaustible world of the smallest forms of existence..."
"We were bombarded — this is the best way to put it — by requests from all the medical people and all the colloidal physics people — everybody that had things too small to be seen in a light microscope. We quickly realized that two graduate students working in a makeshift lab with a makeshift instrument couldn't satisfy the needs for this tool. "
"Its pictures had for me the effect of the song of a mermaid: irresistible and half transparent."