"Suppose you lived in a world in which the ground was a crossword puzzle. Would you or would you not try to solve the puzzle?""
"I believe that you have to take some intelligent risks to advance science."
"In our case the project was a great risk because for more than fifty years the people had not succeeded to improve the electron optics in spite of severe efforts"
"A lot of the other companies, including GE, told me about their retirement plans and their beautiful new laboratories and not much about electron microscopy, but Zworykin showed me an old abandoned factory building. It was really a decrepit place. He asked me how soon can I build a microscope. "
"The electron microscope is like the monkey wrench on the garage wall; what you do with it is the important thing."
"... fluorescence microscopy in its early years was considered a specialized method which, in the opinion of some, was doomed to fail. "
"Frankly most of the stuff we try just doesn't work"
"There was no physical law to prevent it."